A test developed by researchers in Nottingham is helping doctors diagnose multiple sclerosis (MS) without using a lumbar puncture.
The approach adds around six minutes to a standard MRI scan. It allows clinicians to look closely at lesions in the brain and see whether a vein runs through their centre β a feature that can help distinguish MS from other conditions.
A less invasive option for patients
Experts at the University of Nottingham have worked on the technique for more than 20 years. It is now being used in the city, where medical teams say it has reduced the time needed to reach a diagnosis.
A lumbar puncture involves inserting a needle into the lower back to collect fluid from the spine. The procedure can require a hospital visit and may cause headaches and back pain, making it an unwelcome prospect for people already facing an uncertain diagnosis.
Teresa Needham, from Stapleford, was diagnosed using the MRI option after initially being investigated for a possible stroke. She said she was able to go to work straight after the scan.
The researchers hope the test will be adopted more widely across the UK. Its development builds on Nottinghamβs long history of MRI research, including work led by Sir Peter Mansfield in the 1970s.
Why it matters for Britain
If rolled out more widely, the test could make MS diagnosis quicker and less disruptive for patients, while reducing reliance on an invasive procedure. It also shows how long-running university research can be turned into a practical NHS tool.




